SCHEMBL682829

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18744649	0.84	CNR1 (0.35)	MAPTMEN1KMT2ASIGMAR1CNR1
	SCHEMBL682831	0.83	MAPT (0.34)	MAPTSMN1; SMN2CNR1BCHECNR2
	SCHEMBL705027	0.81	BRD4 (0.39)	GRM4MAPTMEN1KMT2AALDH1A1
	SCHEMBL681760	0.78	HTR4 (0.35)	MAPTMEN1KMT2AALDH1A1HTT
	SCHEMBL15333180	0.75	BRD4 (0.43)	GRM4MAPTMEN1KMT2AHTT
	SCHEMBL23214243	0.75	MAPT (0.45)	MAPTKMT2AALDH1A1HTTSMN1; SMN2
	SCHEMBL25886396	0.73	ADORA2A (0.40)	MAPTMEN1KMT2APPARGNCOA2
	SCHEMBL24117839	0.73	GRM4 (0.46)	GRM4ADORA2AADORA2BALDH1A1CNR1
	SCHEMBL17673297	0.73	MAPT (0.35)	MAPTMEN1KMT2APPARGNCOA2
	SCHEMBL15971226	0.71	RET (0.35)	MAPTMEN1KMT2AALDH1A1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.