SCHEMBL682831

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL682829	0.83	GRM4 (0.37)	MAPTCNR1BCHECNR2SMN1; SMN2
	SCHEMBL18744649	0.81	CNR1 (0.35)	MAPTCNR1BCHECNR2
	SCHEMBL705027	0.75	BRD4 (0.39)	MAPTCNR1
	SCHEMBL681760	0.72	HTR4 (0.35)	MAPTSMN1; SMN2
	SCHEMBL19518242	0.72	JAK1 (0.33)	MAPTCSNK2A1SMN1; SMN2PDE5APDE4D
	SCHEMBL23214243	0.69	MAPT (0.45)	MAPTCNR1SMN1; SMN2
	SCHEMBL15333180	0.69	BRD4 (0.43)	MAPTCNR1PDE10A
	SCHEMBL14689815	0.66	MAPT (0.50)	MAPTCSNK2A1SMN1; SMN2
	SCHEMBL15971226	0.66	RET (0.35)	MAPT
	SCHEMBL24147772	0.65	CNR1 (0.41)	GSK3BCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.