⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258808 | 0.80 | FDPS (0.37) | — | |
| SCHEMBL2283392 | 0.78 | — | — | |
| SCHEMBL1830704 | 0.76 | MAPT (0.35) | — | |
| SCHEMBL234773 | 0.76 | PLA2G1B (0.35) | — | |
| SCHEMBL6910414 | 0.76 | — | — | |
| SCHEMBL16397973 | 0.74 | — | — | |
| SCHEMBL2361412 | 0.74 | DNM1 (0.40) | — | |
| SCHEMBL34567 | 0.73 | — | — | |
| SCHEMBL2839059 | 0.72 | ALDH1A1 (0.39) | — | |
| SCHEMBL8679255 | 0.72 | DNM1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1248838-A4 | POLYAMPHOLYTES FOR DELIVERING POLYIONS TO A CELL | MIRUS CORP (US) | 2004-08-25 | — | — | EP | disclosed |
| EP-1248838-A1 | POLYAMPHOLYTES FOR DELIVERING POLYIONS TO A CELL | Mirus Corporation (US) | 2002-10-16 | — | — | EP | disclosed |
| WO-2001049841-A1 | POLYAMPHOLYTES FOR DELIVERING POLYIONS TO A CELL | MIRUS CORPORATION (US) | 2001-07-12 | — | — | WO | disclosed |