Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL281723 | 0.75 | RAF1 (0.42) | GSK3B | |
| SCHEMBL6828627 | 0.74 | DAO (0.37) | — | |
| SCHEMBL27525346 | 0.73 | KDM4E (0.37) | — | |
| SCHEMBL833851 | 0.71 | DAO (0.46) | — | |
| SCHEMBL6223675 | 0.65 | DAO (0.39) | — | |
| SCHEMBL24212569 | 0.64 | RAF1 (0.39) | — | |
| SCHEMBL7253081 | 0.64 | KDM4E (0.35) | — | |
| SCHEMBL3376870 | 0.61 | NQO1 (0.39) | — | |
| SCHEMBL15327693 | 0.61 | NOTUM (0.33) | — | |
| SCHEMBL15111027 | 0.61 | NOTUM (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442030-A1 | THIOPENE- AMD THIAZOLESULFONAMIDES AS ANTINEOPLASTIC AGENTS | ELI LILLY AND COMPANY (US) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003035629-A1 | THIOPENE- AMD THIAZOLESULFONAMIDES AS ANTINEOPLASTIC AGENTS | ELI LILLY AND COMPANY (US) | 2003-05-01 | — | — | WO | disclosed |