Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.30 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6223675 | 0.86 | DAO (0.39) | NOTUMHPGDDAONPC1PKM | |
| Hydrochloric Acid SCHEMBL10800905 | 0.84 | CFTR (0.37) | NOTUML3MBTL1HPGDTSHRMAPK1 | |
| SCHEMBL10805519 | 0.78 | GAA (0.32) | NOTUML3MBTL1CUL4ANPC1PKM | |
| SCHEMBL281723 | 0.73 | RAF1 (0.42) | NOTUML3MBTL1TSHRNPC1PKM | |
| SCHEMBL10801134 | 0.72 | ALDH1A1 (0.39) | L3MBTL1HPGDATMNPC1PKM | |
| SCHEMBL6205872 | 0.67 | HSD17B10 (0.34) | L3MBTL1HPGDTSHRCUL4AKDM4E | |
| SCHEMBL6207825 | 0.65 | HSD17B10 (0.33) | HPGDTSHRCUL4AKDM4ETDP1 | |
| SCHEMBL833851 | 0.65 | DAO (0.46) | NOTUMHPGDMAPK1NPSR1DAO | |
| SCHEMBL3672729 | 0.63 | KDM4E (0.37) | HPGDTSHRNPC1KDM4ELMNA | |
| SCHEMBL15453564 | 0.63 | CES2 (0.45) | NOTUMMAPK1NPSR1P2RX1TMPRSS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599203-B1 | 1,3-SUBSTITUTED CYCLOALKYL DERIVATIVES CONTAINING ACIDIC, MAINLY HETEROCYCLIC GROUPS, CORRESPONDING PRODUCTION METHOD AND USE OF SAID DERIVATIVES AS MEDICAMENTS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2013-10-23 | — | — | EP | disclosed |