Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 13/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831133 | 0.85 | TERT (0.58) | TERTALDH1A1MAPTGAACYP1A2 | |
| SCHEMBL6831103 | 0.81 | TERT (0.57) | TERTALDH1A1MAPTGAACYP1A2 | |
| SCHEMBL6829502 | 0.79 | ALDH1A1 (0.74) | TERTALDH1A1MAPTGAACYP1A2 | |
| SCHEMBL6829097 | 0.79 | TERT (0.58) | TERTALDH1A1MAPTGAACYP1A2 | |
| SCHEMBL6826477 | 0.79 | TERT (0.65) | TERTALDH1A1MAPTGAACYP1A2 | |
| SCHEMBL6830993 | 0.78 | TERT (0.48) | TERTALDH1A1MAPTCYP1A2 | |
| SCHEMBL6828768 | 0.76 | ALDH1A1 (0.52) | TERTALDH1A1MAPTGAACYP1A2 | |
| SCHEMBL6925421 | 0.74 | GRM4 (0.59) | TERTALDH1A1MAPTGAANPC1 | |
| SCHEMBL6830042 | 0.73 | TERT (1.00) | TERTALDH1A1 | |
| SCHEMBL2348998 | 0.71 | TERT (0.55) | TERTMAPTGAACYP1A2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |