Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 14/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829662 | 0.80 | TERT (0.50) | TERTCYP1A2ALDH1A1HSD17B10MAPT | |
| SCHEMBL6829097 | 0.79 | TERT (0.58) | TERTCYP1A2ALDH1A1MAPT | |
| SCHEMBL6828668 | 0.78 | TERT (0.57) | TERTCYP1A2ALDH1A1MAPT | |
| SCHEMBL6831139 | 0.74 | TERT (0.51) | TERTALDH1A1HSD17B10MAPT | |
| SCHEMBL6831133 | 0.73 | TERT (0.58) | TERTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6921975 | 0.73 | RAB9A (0.38) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6831103 | 0.73 | TERT (0.57) | TERTCYP1A2ALDH1A1MAPT | |
| SCHEMBL27640776 | 0.70 | KMT2A (0.59) | SCN9ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8759715 | 0.70 | RAB9A (0.46) | ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL6925215 | 0.69 | PRSS1 (0.40) | ALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |