Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 4/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TPH1 | P17752 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650052 | 0.83 | KMT2A (0.60) | GAAL3MBTL1MYCNR4A1PTPN1 | |
| SCHEMBL15533384 | 0.81 | ALDH1A1 (0.48) | HRH1CCR3KCNH2GAAL3MBTL1 | |
| SCHEMBL6829549 | 0.81 | NOTUM (0.51) | HRH1CCR3KCNH2GAAL3MBTL1 | |
| SCHEMBL27676401 | 0.81 | ALDH1A1 (0.48) | HRH1CCR3KCNH2GAAL3MBTL1 | |
| SCHEMBL11101441 | 0.80 | KDM4E (0.50) | GAANR4A1NPC1KMT2AALDH1A1 | |
| SCHEMBL11101732 | 0.80 | MYC (0.50) | HRH1CCR3KCNH2MYCNR4A1 | |
| SCHEMBL11102512 | 0.80 | MYC (0.50) | MYCNR4A1ALDH1A1HTTKDM4E | |
| SCHEMBL8048603 | 0.80 | ALDH1A1 (0.61) | L3MBTL1MYCNR4A1ENPP2PTPN1 | |
| SCHEMBL2562249 | 0.77 | GAA (0.43) | HRH1GAASCD5NPC1HTT | |
| SCHEMBL2562246 | 0.77 | GAA (0.43) | HRH1GAASCD5NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |