SCHEMBL8415864

SCHEMBL8415864

C[Si](C)(O)CC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29065871 0.76 FFAR3 (0.41)
SCHEMBL632284 0.76 FFAR3 (0.41)
SCHEMBL442427 0.76
SCHEMBL30203760 0.71
SCHEMBL3420650 0.69
SCHEMBL16554200 0.69
SCHEMBL18692016 0.69
SCHEMBL512417 0.69 FFAR3 (0.35)
SCHEMBL6828843 0.67 LMNA (0.40)
SCHEMBL4074107 0.67 HMGCR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140243286-A1 BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME COFERON, INC. (US) 2014-08-28 US disclosed
US-20140243286-A1 BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME COFERON, INC. (US) 2014-08-28 US disclosed
US-5928631-A ALSO COMPRISING AN AQUEOUS CARRIER, AN OIL PHASE, E.G. EMOLLIENTS, MOISTURIZERS AND SKIN PROTECTANTS, AND SURFACTANT HAVING A HYDROPHILIC/LIPOPHILIC BALANCE OF 8-18; APPLYING TO THE SKIN AND HAIR; FOOD ODORS, GASOLINE ETC; DEODORIZING THE PROCTER & GAMBLE COMPANY (US) 1999-07-27 US disclosed