Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 2/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GABRP | O00591 | 3/20 | 0.41 |
| ▸ | GABRD | O14764 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11484236 | 0.87 | ACLY (0.49) | KDM6BKDM4CACLYKDM4EALDH1A1 | |
| SCHEMBL11488718 | 0.84 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL15638568 | 0.79 | TLR7 (0.44) | KDM6BKDM4CKDM4EALDH1A1HPGD | |
| SCHEMBL11246937 | 0.78 | ACLY (0.45) | ACLYKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7834038 | 0.78 | KDM5B (0.58) | KDM6BKDM4CACLYKDM4EALDH1A1 | |
| SCHEMBL1758986 | 0.78 | ACLY (0.52) | KDM4CACLYKDM4EALDH1A1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27649502 | 0.77 | KDM5B (0.57) | KDM6BKDM4CACLYKDM4EALDH1A1 | |
| SCHEMBL8193624 | 0.77 | POLB (0.45) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL10883702 | 0.76 | ACLY (0.51) | ACLYKDM4EALDH1A1SMN1; SMN2GABRP | |
| SCHEMBL444440 | 0.76 | KDM5B (0.49) | KDM6BKDM4CACLYKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |