Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 2/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834038 | 0.98 | KDM5B (0.58) | KDM5BPPARGHTTKDM4EKDM6B | |
| Benzylamine SCHEMBL1523283 | 0.92 | KDM5B (0.52) | KDM5BPPARGHTTKDM4EKDM6B | |
| SCHEMBL444440 | 0.87 | KDM5B (0.49) | KDM5BPPARGKDM4EKDM6BKDM4A | |
| SCHEMBL26113920 | 0.87 | KDM4C (0.55) | KDM5BPPARGHTTKDM4EKDM4C | |
| SCHEMBL11485899 | 0.86 | ALDH1A1 (0.59) | KDM5BHTTKDM4EALDH1A1HPGD | |
| SCHEMBL11484236 | 0.80 | ACLY (0.49) | KDM4EKDM6BKDM4CALDH1A1HPGD | |
| SCHEMBL2902712 | 0.78 | REN (0.68) | HTTKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL2899932 | 0.78 | KDM4C (0.53) | KDM4EKDM4CALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1523285 | 0.78 | ALDH1A1 (0.43) | HTTKDM4EALDH1A1HPGDCRHBP | |
| SCHEMBL6829015 | 0.77 | KDM6B (0.48) | KDM4EKDM6BKDM4CALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100376572-C | Anti-infective agents | ABBOTT LAB (US) | 2008-03-26 | — | — | CN | disclosed |
| CN-1735612-A | Anti-infective agents | ABBOTT LAB (US) | 2006-02-15 | — | — | CN | disclosed |