Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 16/20 | 0.63 |
| ▸ | KDR | P35968 | 14/20 | 0.63 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | BRAF | P15056 | 2/20 | 0.37 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6829065 | 0.85 | SRC (0.57) | SRCKDREGFRBRAF | |
| SCHEMBL6823702 | 0.82 | SRC (0.58) | SRCKDREGFRBRAFTNNI3K | |
| SCHEMBL6829839 | 0.82 | SRC (0.60) | SRCKDREGFR | |
| SCHEMBL6826661 | 0.81 | SRC (0.69) | SRCKDREGFR | |
| SCHEMBL7132585 | 0.81 | SRC (0.69) | SRCKDREGFR | |
| SCHEMBL6829362 | 0.77 | SRC (1.00) | SRCKDR | |
| SCHEMBL6829415 | 0.77 | SRC (0.60) | SRCKDREGFR | |
| SCHEMBL6829580 | 0.75 | SRC (0.78) | SRCKDR | |
| Trifluoroacetic Acid SCHEMBL6823695 | 0.68 | SRC (0.54) | SRCKDREGFR | |
| SCHEMBL6832867 | 0.67 | SRC (0.79) | SRCKDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108710-A1 | 4-PYRIMIDINYL QUINAZOLINE DERIVATIVES FOR USE IN THE TREATMENT OF TUMOURS | ASTRAZENECA AB (SE) | 2004-12-16 | — | — | WO | disclosed |