Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19019783 | 1.00 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL19019780 | 0.98 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1162378 | 0.93 | TSHR (0.53) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL21555723 | 0.91 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7701376 | 0.89 | TSHR (0.41) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7706289 | 0.89 | TSHR (0.41) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7709308 | 0.89 | TSHR (0.41) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7706303 | 0.88 | ALDH1A1 (0.41) | TSHRTDP1THRBALDH1A1 | |
| SCHEMBL16207848 | 0.87 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16286674 | 0.87 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428856-A1 | Thermoplastic resin composition comprising a crosslinked composition derived from a softening agent for rubber | Riken Technos Corporation (JP) | 2004-06-16 | — | — | EP | disclosed |