Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829110 | 1.00 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL19019780 | 0.98 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1162378 | 0.93 | TSHR (0.53) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL21555723 | 0.91 | TSHR (0.49) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7701376 | 0.89 | TSHR (0.41) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7706289 | 0.89 | TSHR (0.41) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7709308 | 0.89 | TSHR (0.41) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7706303 | 0.88 | ALDH1A1 (0.41) | TSHRTDP1THRBALDH1A1 | |
| SCHEMBL16207848 | 0.87 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16286674 | 0.87 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428664-B | Method for producing (meth) acrylate compound | 株式会社可乐丽 | 2020-07-10 | — | — | CN | disclosed |
| CN-107849203-B | (meth) acrylic block copolymer | 株式会社可乐丽 | 2020-04-24 | — | — | CN | disclosed |
| EP-3327053-B1 | (METH)ACRYLIC BLOCK COPOLYMER | KURARAY CO (JP) | 2020-03-25 | — | — | EP | disclosed |
| US-10426712-B2 | Dental polymerizable composition | KURARAY NORITAKE DENTAL INC. (JP) | 2019-10-01 | — | — | US | disclosed |
| EP-3269701-B1 | METHOD FOR PRODUCING (METH)ACRYLATE ESTER COMPOUNDS | KURARAY CO (JP) | 2019-05-08 | — | — | EP | disclosed |
| US-20180208700-A1 | (METH)ACRYLIC BLOCK COPOLYMER | KURARAY CO., LTD. (JP) | 2018-07-26 | — | — | US | disclosed |
| EP-3327053-A1 | (METH)ACRYLIC BLOCK COPOLYMER | Kuraray Co., Ltd. (JP) | 2018-05-30 | — | — | EP | disclosed |
| US-20170290746-A1 | DENTAL POLYMERIZABLE COMPOSITION | KURARAY NORITAKE DENTAL INC. (JP) | 2017-10-12 | — | — | US | disclosed |
| US-20170240739-A1 | ACTIVE ENERGY RAY CURABLE COMPOSITIONS | KURARAY CO., LTD. (JP) | 2017-08-24 | — | — | US | disclosed |
| EP-3195846-A1 | DENTAL POLYMERIZABLE COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2017-07-26 | — | — | EP | disclosed |
| EP-3184563-A1 | ACTIVE ENERGY RAY-CURABLE COMPOSITION | Kuraray Co., Ltd. (JP) | 2017-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10426712-B2 | Dental polymerizable composition | MMAB, GRIN2B, CAD | TSHR 3756/4885POLB 287/4885APEX1 444/4885 |
| US-20170290746-A1 | DENTAL POLYMERIZABLE COMPOSITION | MMAB, GRIN2B, CAD | TSHR 3756/4885POLB 287/4885APEX1 444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.