SCHEMBL6829260

SCHEMBL6829260

Cc1ccc(C(=O)Nc2cc[c]c(C(C)(C)C)c2)c(N2CCCCC2)n1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCN10A Q9Y5Y9 10/20 0.63
KIF18A Q8NI77 9/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6831083 0.90 SCN10A (0.51) SCN10AKIF18A
SCHEMBL6826008 0.84 SCN10A (0.61) SCN10AKIF18A
SCHEMBL6829403 0.82 SCN10A (0.63) SCN10AKIF18A
SCHEMBL23779529 0.77 SCN10A (1.00) SCN10AKIF18A
SCHEMBL29615275 0.77 SCN10A (1.00) SCN10AKIF18A
SCHEMBL6830990 0.77 MEN1 (0.40) SCN10A
SCHEMBL29256616 0.76 SCN10A (0.67) SCN10A
SCHEMBL31037390 0.76 SCN10A (0.67) SCN10A
SCHEMBL29256590 0.76 SCN10A (0.67) SCN10A
SCHEMBL31037437 0.74 SCN10A (0.66) SCN10AKIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004039795-A2 AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-05-13 WO disclosed