Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 6/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KIF18A | Q8NI77 | 3/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825969 | 0.89 | SCN10A (0.52) | SCN10AALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL6828987 | 0.89 | SCN10A (0.52) | SCN10AL3MBTL1ALDH1A1KDM4EKIF18A | |
| SCHEMBL6828922 | 0.84 | SCN10A (0.48) | SCN10AL3MBTL1ALDH1A1MAPTKDM4E | |
| SCHEMBL6829260 | 0.82 | SCN10A (0.63) | SCN10AKIF18A | |
| SCHEMBL29256637 | 0.79 | SCN10A (0.66) | SCN10AKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31037437 | 0.79 | SCN10A (0.66) | SCN10AKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29256590 | 0.79 | SCN10A (0.67) | SCN10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29256616 | 0.79 | SCN10A (0.67) | SCN10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31037390 | 0.79 | SCN10A (0.67) | SCN10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6825984 | 0.79 | ALDH1A1 (0.74) | SCN10AL3MBTL1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |