SCHEMBL6831083

SCHEMBL6831083

Cc1ccc(C(=O)Nc2cc[c]c(C(C)(C)C)c2)c(N2CCSCC2)n1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SCN10A Q9Y5Y9 3/20 0.51
KIF18A Q8NI77 16/20 0.42
PTPN11 Q06124 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6829260 0.90 SCN10A (0.63) SCN10AKIF18A
SCHEMBL6828987 0.84 SCN10A (0.52) SCN10AKIF18APTPN11
SCHEMBL6828922 0.78 SCN10A (0.48) SCN10AKIF18APTPN11
SCHEMBL6647476 0.75 SCN10A (0.46) SCN10AKIF18APTPN11
SCHEMBL6830990 0.75 MEN1 (0.40) SCN10A
SCHEMBL6645593 0.75 MAPT (0.48) SCN10APTPN11
SCHEMBL6826008 0.74 SCN10A (0.61) SCN10AKIF18A
SCHEMBL6829403 0.73 SCN10A (0.63) SCN10AKIF18APTPN11
SCHEMBL6825969 0.70 SCN10A (0.52) SCN10AKIF18A
SCHEMBL6643114 0.70 SCN10A (0.44) SCN10AKIF18APTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004039795-A2 AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-05-13 WO disclosed