Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KIF18A | Q8NI77 | 13/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829260 | 0.84 | SCN10A (0.63) | SCN10AKIF18A | |
| SCHEMBL6825984 | 0.82 | ALDH1A1 (0.74) | SCN10AMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL6830902 | 0.77 | VCP (0.41) | MEN1KMT2AALDH1A1KIF18A | |
| SCHEMBL31610168 | 0.74 | SCN10A (0.69) | SCN10AMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL16217083 | 0.74 | ALDH1A1 (0.65) | SCN10AMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL6831083 | 0.74 | SCN10A (0.51) | SCN10AKIF18A | |
| SCHEMBL6829454 | 0.73 | KMT2A (0.64) | SCN10AMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL28059131 | 0.73 | ALDH1A1 (0.61) | SCN10AMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL30115277 | 0.71 | KIF18A (1.00) | SCN10AALDH1A1KIF18A | |
| SCHEMBL22963026 | 0.71 | KIF18A (1.00) | SCN10AALDH1A1KIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |