Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 11/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831113 | 0.76 | MAPT (0.62) | TERTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL6828985 | 0.75 | SMN1; SMN2 (0.51) | NPC1POLBHTTRAB9ASMN1; SMN2 | |
| SCHEMBL6829662 | 0.75 | TERT (0.50) | TERTALDH1A1MAPT | |
| SCHEMBL6921427 | 0.75 | NPC1 (0.52) | TERTNPC1POLBHTTRAB9A | |
| SCHEMBL6829663 | 0.74 | TERT (0.59) | TERTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL22281464 | 0.73 | TERT (0.53) | TERTPOLB | |
| SCHEMBL6831025 | 0.72 | RAB9A (0.60) | TERTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL6831144 | 0.72 | KMT2A (0.55) | NPC1HTTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6831237 | 0.70 | TERT (0.58) | TERTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL12374823 | 0.69 | TERT (0.57) | TERTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |