Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 7/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831237 | 0.87 | TERT (0.58) | TERTPOLBRAB9AKMT2ALMNA | |
| SCHEMBL6831113 | 0.87 | MAPT (0.62) | TERTPOLBRAB9AKMT2ALMNA | |
| SCHEMBL6925421 | 0.84 | GRM4 (0.59) | TERTPOLBRAB9AKMT2ALMNA | |
| SCHEMBL7126167 | 0.80 | RAB9A (0.54) | TERTPOLBRAB9AKMT2ALMNA | |
| SCHEMBL6829484 | 0.78 | TERT (0.56) | TERTPOLBRAB9AKMT2ALMNA | |
| SCHEMBL22281464 | 0.77 | TERT (0.53) | TERTPOLB | |
| SCHEMBL13550114 | 0.75 | KMT2A (0.62) | RAB9AKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL6922934 | 0.75 | TERT (1.00) | TERTLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6831133 | 0.75 | TERT (0.58) | TERTRAB9AKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL6829329 | 0.74 | TERT (0.48) | TERTPOLBRAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |