Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282589 | 0.84 | ALDH1A1 (0.62) | ALDH1A1LMNAGAAMAPTSMN1; SMN2 | |
| SCHEMBL5652459 | 0.81 | ALDH1A1 (0.76) | ALDH1A1LMNAGAAMAPTSMN1; SMN2 | |
| SCHEMBL30346122 | 0.77 | ALDH1A1 (0.49) | ALDH1A1LMNAGAASMN1; SMN2CYP1A2 | |
| SCHEMBL28504649 | 0.77 | HTT (0.50) | ALDH1A1LMNAGAASMN1; SMN2CYP1A2 | |
| SCHEMBL26092046 | 0.77 | ALDH1A1 (0.49) | ALDH1A1LMNAGAASMN1; SMN2CYP1A2 | |
| SCHEMBL22495332 | 0.76 | SLC6A9 (0.61) | ALDH1A1LMNAGAASLC6A9SLC6A5 | |
| SCHEMBL30410222 | 0.74 | ALDH1A1 (0.61) | ALDH1A1LMNAGAASMN1; SMN2CYP1A2 | |
| SCHEMBL30464734 | 0.74 | ALDH1A1 (0.66) | ALDH1A1LMNAGAAMAPTSMN1; SMN2 | |
| SCHEMBL2461666 | 0.74 | ALDH1A1 (0.66) | ALDH1A1LMNAGAAMAPTSMN1; SMN2 | |
| SCHEMBL15961236 | 0.74 | SIRT6 (0.59) | ALDH1A1LMNAGAASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046118-A2 | 2-4-(DI-PHENYL-AMINO)-PYRIMIDINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-06-03 | — | — | WO | disclosed |