Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829760 | 0.87 | LTA4H (0.51) | KMT2AMEN1SMN1; SMN2LTA4HKDM4E | |
| SCHEMBL6829815 | 0.87 | MEN1 (0.51) | KMT2AMEN1MAPTLTA4HALDH1A1 | |
| SCHEMBL6829528 | 0.86 | KMT2A (0.50) | KMT2AMEN1GAAMAPTLTA4H | |
| SCHEMBL6829910 | 0.86 | MEN1 (0.50) | KMT2AMEN1MAPTLTA4HCA12 | |
| SCHEMBL1520986 | 0.83 | CA12 (0.49) | KMT2ASMN1; SMN2CA12CA7CA9 | |
| SCHEMBL10042377 | 0.83 | CA12 (0.49) | KMT2ASMN1; SMN2CA12CA7CA9 | |
| SCHEMBL11375764 | 0.80 | PPARG (0.54) | CA12CA7CA9CA14RIPK1 | |
| SCHEMBL6831514 | 0.79 | AOC3 (0.49) | GAAMAPTLTA4HALDH1A1SLC6A9 | |
| SCHEMBL28391707 | 0.77 | LMNA (0.52) | GAAKDM4EALDH1A1RIPK1AOC3 | |
| SCHEMBL6830431 | 0.77 | UTS2R (0.42) | KMT2ASLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043921-A1 | NOVEL PROCESS FOR THE PREPARATION OF 4-ARYL-3-HYDROXYMETHYL-1-METHYLPIPERIDINES. | NATCO PHARMA LIMITED (IN) | 2004-05-27 | — | — | WO | disclosed |