SCHEMBL6829454

SCHEMBL6829454

CC1CCN(c2ncccc2C(=O)Nc2cc[c]cc2)CC1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.64
ALDH1A1 P00352 2/20 0.61
L3MBTL1 Q9Y468 1/20 0.56
NPC1 O15118 1/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
RAB9A P51151 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
KIF18A Q8NI77 9/20 0.52
MEN1 O00255 2/20 0.50
SCN10A Q9Y5Y9 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6825984 0.87 ALDH1A1 (0.74) KMT2AALDH1A1L3MBTL1MAPTRAB9A
SCHEMBL6825969 0.82 SCN10A (0.52) KMT2AALDH1A1NPC1GAAMAPT
SCHEMBL6645164 0.80 ALDH1A1 (0.54) KMT2AALDH1A1L3MBTL1NPC1GAA
SCHEMBL6644178 0.78 L3MBTL1 (0.56) KMT2AALDH1A1L3MBTL1NPC1GAA
SCHEMBL6829453 0.77 KMT2A (0.58) KMT2AALDH1A1L3MBTL1NPC1GAA
SCHEMBL6830890 0.76 KMT2A (0.54) KMT2AALDH1A1L3MBTL1KIF18AMEN1
SCHEMBL6647790 0.76 KMT2A (0.51) KMT2AALDH1A1L3MBTL1NPC1GAA
SCHEMBL6647795 0.74 KMT2A (0.51) KMT2AALDH1A1L3MBTL1MAPTKIF18A
SCHEMBL6644731 0.74 ALDH1A1 (0.45) KMT2AALDH1A1L3MBTL1NPC1GAA
SCHEMBL13116729 0.73 ALDH1A1 (0.61) KMT2AALDH1A1L3MBTL1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004039795-A2 AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-05-13 WO disclosed