Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 14/20 | 0.64 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.59 |
| ▸ | GCGR | P47871 | 1/20 | 0.57 |
| ▸ | KIF11 | P52732 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL464630 | 1.00 | LMNA (0.65) | LMNAMAPTMAPK14MAPK10GCGR | |
| SCHEMBL26548404 | 0.86 | MAPK14 (0.53) | LMNAMAPTMAPK14MAPK10GCGR | |
| SCHEMBL26547982 | 0.86 | MAPK14 (0.53) | LMNAMAPTMAPK14MAPK10GCGR | |
| SCHEMBL26548589 | 0.84 | MAPK14 (0.52) | LMNAMAPTMAPK14MAPK10GCGR | |
| SCHEMBL10000032 | 0.84 | MAPT (0.92) | LMNAMAPTGCGRKIF11KDM4E | |
| SCHEMBL135626 | 0.84 | MAPT (0.92) | LMNAMAPTGCGRKIF11KDM4E | |
| SCHEMBL6337863 | 0.83 | MAPK14 (0.60) | MAPK14MAPK10GCGRMAPK13MAPK12 | |
| SCHEMBL9208657 | 0.82 | LTA4H (0.52) | LMNAMAPTMAPK14MAPK10GCGR | |
| SCHEMBL18770326 | 0.81 | CYP17A1 (0.68) | MAPK14GCGR | |
| SCHEMBL28802099 | 0.81 | KDM4E (0.50) | MAPK14MAPK10GCGRKDM4EAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406909-A1 | LUMINESCENT LANTHANIDE COMPLEXES WITH IMINE LIGANDS AND DEVICES MADE WITH SUCH COMPLEXES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-04-14 | — | — | EP | claimed |
| WO-2003008424-A1 | LUMINESCENT LANTHANIDE COMPLEXES WITH IMINE LIGANDS AND DEVICES MADE WITH SUCH COMPLEXES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-01-30 | — | — | WO | claimed |