SCHEMBL26548404

SCHEMBL26548404

Fc1ccc(-c2ccc(-c3ccc4cc(-c5ccc(-c6ccncc6)cc5)ccc4c3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 9/20 0.53
MAPK10 P53779 1/20 0.53
CYP3A4 P08684 3/20 0.50
CYP17A1 P05093 2/20 0.50
CYP11B1 P15538 2/20 0.50
KDM4E B2RXH2 1/20 0.50
AR P10275 1/20 0.50
CYP21A2 P08686 1/20 0.50
DYRK1A Q13627 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
CYP11B2 P19099 2/20 0.47
GCGR P47871 3/20 0.47
MAPK13 O15264 1/20 0.47
PRKD3 O94806 1/20 0.47
MAP4K4 O95819 1/20 0.47
FRK P42685 1/20 0.47
MAPK9 P45984 1/20 0.47
CSNK1A1 P48729 1/20 0.47
CSNK1D P48730 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26547982 1.00 MAPK14 (0.53) MAPK14MAPK10CYP3A4CYP17A1CYP11B1
SCHEMBL26548903 0.94 MAPK14 (0.52) MAPK14MAPK10CYP3A4CYP17A1CYP11B1
SCHEMBL26548589 0.94 MAPK14 (0.52) MAPK14MAPK10CYP3A4CYP17A1CYP11B1
SCHEMBL9612000 0.89 LMNA (0.61) MAPK10CYP3A4CYP17A1CYP11B1DYRK1A
SCHEMBL464630 0.86 LMNA (0.65) MAPK14MAPK10KDM4EARLMNA
SCHEMBL6829472 0.86 LMNA (0.65) MAPK14MAPK10KDM4EARLMNA
SCHEMBL26548510 0.86 PGR (0.55)
SCHEMBL26548124 0.86 PGR (0.55)
SCHEMBL26548202 0.85 KDM4E (0.46) MAPK14MAPK10CYP3A4CYP11B1KDM4E
SCHEMBL23924863 0.84 LMNA (0.55) MAPK10CYP3A4CYP17A1CYP11B1DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 MAPK14 3890/4885MAPK10 1968/4885CYP3A4 1274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.