Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91356 | 0.83 | TAAR1 (0.50) | AKR1B1SMN1; SMN2TAAR1POLBKMT2A | |
| SCHEMBL3790392 | 0.79 | GABRA1 (0.46) | AKR1B1SMN1; SMN2TAAR1GABRA1GABRB2 | |
| SCHEMBL186267 | 0.76 | GABRA1 (0.48) | TAAR1GABRA1GABRB2HTTNPSR1 | |
| SCHEMBL10180159 | 0.74 | TAAR1 (0.43) | AKR1B1SMN1; SMN2TAAR1POLBKMT2A | |
| SCHEMBL726569 | 0.74 | TAAR1 (0.43) | AKR1B1SMN1; SMN2TAAR1POLBKDM4E | |
| SCHEMBL659716 | 0.74 | NOS3 (0.38) | TAAR1GABRA1GABRB2HTTLMNA | |
| SCHEMBL6988345 | 0.74 | TAAR1 (0.43) | AKR1B1SMN1; SMN2TAAR1POLBKMT2A | |
| SCHEMBL22427663 | 0.74 | MAPT (0.41) | AKR1B1SMN1; SMN2TAAR1POLBKMT2A | |
| SCHEMBL14498154 | 0.74 | GABRA1 (0.52) | AKR1B1SMN1; SMN2TAAR1GABRA1GABRB2 | |
| SCHEMBL15302023 | 0.73 | TAAR1 (0.41) | AKR1B1SMN1; SMN2TAAR1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6746757-B1 | Multilayered molding | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2004-06-08 | — | — | US | disclosed |
| EP-0852604-B1 | A POLYPHENYLENE OXIDE DELIVERY SYSTEM FOR ADHESIVE COMPOSITIONS | ARIZONA CHEM (US) | 2002-04-10 | — | — | EP | disclosed |
| US-5910526-A | HEATING AND MIXING PREBLEND COMPRISING A POLYPHENYLENE ETHER AND B-BLOCK COMPATIBLE RESIN TOGETHER WITH STYRENIC-CONJUGATED DIENE-STRYRENIC-A-B-A BLOCK POLYMER; HIGHER TEMPERAURE HOT MELT ADHESIVES | ARIZONA CHEMICAL COMPANY (US) | 1999-06-08 | — | — | US | disclosed |
| US-5807915-A | HEAT RESISTANCE | ARIZONA CHEMICAL COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| EP-0852604-A4 | — | — | 1998-08-26 | — | — | EP | disclosed |
| US-5789474-A | HOT MELT ADHESIVE | ARIZONA CHEMICAL COMPANY (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0852604-A1 | A POLYPHENYLENE OXIDE DELIVERY SYSTEM FOR ADHESIVE COMPOSITIONS | ARIZONA CHEMICAL COMPANY (US) | 1998-07-15 | — | — | EP | disclosed |
| EP-0381056-B1 | Method for preparing an impact resistant thermoplastic resin composition | MITSUBISHI CHEM CORP (JP) | 1997-09-03 | — | — | EP | disclosed |
| WO-1997011997-A1 | A POLYPHENYLENE OXIDE DELIVERY SYSTEM FOR ADHESIVE COMPOSITIONS | ARIZONA CHEMICAL COMPANY (US) | 1997-04-03 | — | — | WO | disclosed |
| EP-0520146-B1 | Process for preparing a thermoplastic resin composition | MITSUBISHI CHEM CORP (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5091473-A | Polyamide, polyphenylene ether, block polymer, unsaturated acid or anhydride dispension, hydrogenated impact strength, rigidity, heat resistance | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0454156-A2 | Thermoplastic resin composition | MITSUBISHI CHEMICAL CORPORATION (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-5026787-A | Blends of polyphenylene ether, polyamides, unsaturated compounds | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-06-25 | — | — | US | disclosed |
| US-5001181-A | polyamide blends with dispersed particles of polyphenylene ether which contain dispersed filler particles; strength, flexibility, solvent resistance | MITSUBISHI PETROCHEMICAL COMPANY, LTD. (JP) | 1991-03-19 | — | — | US | disclosed |
| EP-0415344-A1 | Resin composition and process for preparing it | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| EP-0381056-A2 | Impact resistant thermoplastic resin composition | MITSUBISHI CHEMICAL CORPORATION (JP) | 1990-08-08 | — | — | EP | disclosed |
| EP-0067217-A4 | COMPOSITIONS OF POLYPHENYLENE OXIDES WITH EPDM-SILICONE RUBBER. | GEN ELECTRIC (US) | 1983-05-16 | — | — | EP | disclosed |
| EP-0067217-A1 | COMPOSITIONS OF POLYPHENYLENE OXIDES WITH EPDM-SILICONE RUBBER | GENERAL ELECTRIC COMPANY (US) | 1982-12-22 | — | — | EP | disclosed |
| US-4365042-A | Compositions of polyphenylene oxides with EPDM-silicone rubber | GENERAL ELECTRIC COMPANY (US) | 1982-12-21 | — | — | US | disclosed |
| WO-1982002204-A1 | COMPOSITIONS OF POLYPHENYLENE OXIDES WITH EPDM-SILICONE RUBBER | GEN ELECTRIC (US) | 1982-07-08 | — | — | WO | disclosed |