Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10180159 | 0.90 | TAAR1 (0.43) | TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6 | |
| SCHEMBL3790392 | 0.85 | GABRA1 (0.46) | TAAR1AKR1B1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL6988345 | 0.85 | TAAR1 (0.43) | TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6 | |
| SCHEMBL726569 | 0.85 | TAAR1 (0.43) | TAAR1AKR1B1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL3791097 | 0.83 | ALDH1A1 (0.52) | TAAR1AKR1B1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL14370502 | 0.83 | TAAR1 (0.41) | TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6 | |
| SCHEMBL7950681 | 0.83 | TAAR1 (0.41) | TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6 | |
| SCHEMBL6829665 | 0.83 | AKR1B1 (0.43) | TAAR1AKR1B1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL11462339 | 0.83 | TAAR1 (0.41) | TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6 | |
| SCHEMBL15302023 | 0.83 | TAAR1 (0.41) | TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400172-A2 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | Incyte Holdings Corporation (US) | 2024-07-17 | — | — | EP | disclosed |
| US-20240228495-A1 | Tricyclic Inhibitors of Influenza Virus Endonuclease | STANFORD RES INST INT (US) | 2024-07-11 | — | — | US | disclosed |
| WO-2024139260-A1 | ALLICIN DERIVATIVES, PREPARATION METHOD THEREFOR, AND USES THEREOF | 成都新朝阳作物科学股份有限公司 | 2024-07-04 | — | — | WO | disclosed |
| CN-118139910-A | Linear block copolymers and curable thermosetting compositions comprising the same | 高新特殊工程塑料全球技术有限公司 | 2024-06-04 | — | — | CN | disclosed |
| WO-2024010810-A2 | FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF | CIDARA THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |
| US-20230399299-A1 | ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE | AMYGDALA NEUROSCIENCES, INC. (US) | 2023-12-14 | — | — | US | disclosed |
| US-20230399307-A1 | ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE | AMYGDALA NEUROSCIENCES, INC. (US) | 2023-12-14 | — | — | US | disclosed |
| EP-3838903-B1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVE AS JANUS KINASE INHIBITOR | INCYTE HOLDINGS CORP (US) | 2023-11-22 | — | — | EP | disclosed |
| CN-116947720-A | Allicin derivative and preparation method and application thereof | 成都新朝阳作物科学股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2023-10-26 | — | — | US | disclosed |
| EP-1475374-A1 | THIADIAZOLE COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-10 | — | — | EP | disclosed |
| WO-2004085408-A1 | 2, 3, 6-TRISUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2004-10-07 | — | — | WO | disclosed |
| US-20040077669-A1 | Pyrimidine compounds and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-04-22 | — | — | US | disclosed |
| US-5081112-A | Administering an aryl phosphonate carboxamide | OTSUKA PHARMACEUTICAL FACTORY INC. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0071833-B1 | PROCESS FOR PRODUCING 4-BENZOYLPYRAZOLES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |
| EP-0186250-A1 | Stabilization of flame retardant polycarbonate-polyester compositions | GENERAL ELECTRIC COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |
| US-4560814-A | Process for alkylating halogenated and trifluoromethylated benzene compounds | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-12-24 | — | — | US | disclosed |
| US-4555540-A | PHOSPHONIC ACID | GENERAL ELECTRIC COMPANY (US) | 1985-11-26 | — | — | US | disclosed |
| US-4415739-A | Process for producing 4-benzoylpyrazoles | ISHIHARA SANGYO KAISHA LTD. (JP) | 1983-11-15 | — | — | US | disclosed |
| EP-0071833-A1 | Process for producing 4-benzoylpyrazoles | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399307-A1 | ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE | ALDH1A1, ALDH2, ALDH3A1 | TAAR1 132/4885AKR1B1 190/4885SMN1; SMN2 2558/4885 |
| US-20040077669-A1 | Pyrimidine compounds and their use | TYMP, TYMS, DPYD | TAAR1 2360/4885AKR1B1 2117/4885SMN1; SMN2 2180/4885 |
| US-20240228495-A1 | Tricyclic Inhibitors of Influenza Virus Endonuclease | RNASEH1, RNASEL, DNASE1 | TAAR1 3181/4885AKR1B1 1322/4885SMN1; SMN2 4726/4885 |
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | DDT, ACHE, AHR | TAAR1 316/4885AKR1B1 3026/4885SMN1; SMN2 4164/4885 |
| US-20230399299-A1 | ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE | ALDH1A1, ALDH2, ALDH3A1 | TAAR1 146/4885AKR1B1 172/4885SMN1; SMN2 2462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.