SCHEMBL587834

SCHEMBL587834

CC(Cl)c1ccccc1Sc1ccccc1C(C)Cl

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.34
GABRB2 P47870 2/20 0.34
P4HB P07237 1/20 0.32
TSHR P16473 2/20 0.31
CYP1A2 P05177 2/20 0.31
CYP3A4 P08684 2/20 0.31
FAAH O00519 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
PTGS1 P23219 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
HTR2B P41595 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30389926 0.80 GABRA1 (0.48) GABRA1GABRB2TSHRCYP1A2CYP3A4
SCHEMBL3911665 0.80 TSHR (0.38) TSHR
SCHEMBL4808650 0.80 GABRA1 (0.48) GABRA1GABRB2TSHRCYP1A2CYP3A4
SCHEMBL2865478 0.79 GABRA1 (0.43) GABRA1GABRB2TSHRCYP1A2CYP3A4
SCHEMBL1424464 0.79 TSHR (0.35) TSHRLMNAHPGDBLMMAOA
SCHEMBL588784 0.76 GABRA1 (0.39) GABRA1GABRB2P4HBTSHRCYP1A2
SCHEMBL10621286 0.76
SCHEMBL5422503 0.76 GABRA1 (0.34) GABRA1GABRB2P4HBTSHRCYP1A2
SCHEMBL4143745 0.76 P2RX7 (0.37) GABRA1GABRB2P4HBTSHRCYP1A2
SCHEMBL6829698 0.75 GABRA1 (0.37) GABRA1GABRB2TSHRCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4545625-A1 REMOVING TOXIC CHEMICALS FROM CONTAMINATED SURFACES Guild Associates, Inc. (US) 2025-04-30 EP disclosed
US-20250121237-A1 Removing Toxic Chemicals from Contaminated Surfaces Guild Associates Inc. (US) 2025-04-17 US disclosed
CN-115772103-B Method for preparing sulfoxide compound by catalytic oxidation of thioether 华东师范大学 2025-04-01 CN disclosed
CN-112533934-B Polyoxometallate compounds exhibiting bright emissions and methods of making same 纳米2D材料有限公司 2024-07-19 CN disclosed
WO-2024114161-A1 METHOD FOR PREPARING SULFOXIDE COMPOUND BY CATALYTICALLY OXIDIZING SULFIDE 华东师范大学 2024-06-06 WO disclosed
CN-115772103-A Method for preparing sulfoxide compound by catalytic oxidation of thioether 华东师范大学 2023-03-10 CN disclosed
CN-108623581-B Method for preparing paninula compound 中国海洋大学 2021-10-22 CN disclosed
CN-112533934-A Polyoxometallate compounds exhibiting bright emission and methods of making the same 纳米2D材料有限公司 2021-03-19 CN disclosed
US-10828873-B1 Textile composite having sorptive and reactive properties against toxic agents BATTELLE MEMORIAL INSTITUTE (US) 2020-11-10 US disclosed
US-10773114-B1 Zirconium hydroxide-based slurry for decontamination and detoxification THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2020-09-15 US disclosed
US-6197965-B1 POLYARYLALKYLAMINO-SUBSTITUED PYRIDINE DERIVATIVES; DRUGS, MEDICINE, DIAGNOSTICS ISIS PHARMACEUTICALS, INC. 2001-03-06 US disclosed
EP-0817787-A4 NITROGENOUS MACROCYCLIC COMPOUNDS ISIS PHARMACEUTICALS INC (US) 2000-09-13 EP disclosed
CN-1241570-A New process for preparation of organosilanes functionalised in the 3-position DEGUSSA (DE) 2000-01-19 CN disclosed
WO-1998010286-A1 METHODS FOR PROCESSING CHEMICAL COMPOUNDS HAVING REACTIVE FUNCTIONAL GROUPS ISIS PHARMACEUTICALS, INC. (US) 1998-03-12 WO disclosed
WO-1998005961-A1 COMPOUNDS HAVING A PLURALITY OF NITROGENOUS SUBSTITUENTS ISIS PHARMACEUTICALS, INC. (US) 1998-02-12 WO disclosed
EP-0817787-A1 NITROGENOUS MACROCYCLIC COMPOUNDS ISIS PHARMACEUTICALS, INC. (US) 1998-01-14 EP disclosed
WO-1996030377-A1 NITROGENOUS MACROCYCLIC COMPOUNDS ISIS PHARMACEUTICALS, INC. (US) 1996-10-03 WO disclosed
US-4524073-A β-Lactam compounds BEECHAM GROUP P.1.C. (GB) 1985-06-18 US disclosed
US-4449005-A REACTING A CHLOROETHYL SULFIDE AND QUATERNARY AMMONIUM OR QUATERNARY PHOSPHONIUM FLUORIDE TO PRODUCE A VINYL SULFIDE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1984-05-15 US disclosed
EP-0101199-A1 Beta-lactam compounds BEECHAM GROUP PLC (GB) 1984-02-22 EP disclosed