Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172197 | 0.75 | PARP1 (0.36) | PARP1MEN1LMNAMAPTKMT2A | |
| SCHEMBL8651078 | 0.63 | GAA (0.57) | PARP1MEN1LMNAMAPTKMT2A | |
| SCHEMBL22133439 | 0.62 | — | — | |
| SCHEMBL22133445 | 0.62 | — | — | |
| SCHEMBL22131425 | 0.60 | MAPT (0.37) | PARP1MEN1LMNAMAPTKMT2A | |
| SCHEMBL22134197 | 0.60 | MAPT (0.37) | PARP1MEN1LMNAMAPTKMT2A | |
| SCHEMBL23722589 | 0.60 | PARP1 (0.50) | PARP1MEN1LMNAMAPTKMT2A | |
| SCHEMBL6097831 | 0.60 | PARP1 (0.50) | PARP1MEN1LMNAMAPTKMT2A | |
| SCHEMBL7063218 | 0.60 | PARP1 (0.41) | PARP1MEN1LMNAMAPTKMT2A | |
| SCHEMBL6097826 | 0.60 | PARP1 (0.41) | PARP1MEN1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5909114-A | Coulometric analysis method and a device therefor | NAKANO VINEGAR CO., LTD. (JP) | 1999-06-01 | — | — | US | claimed |
| WO-2020027024-A1 | PHOTOSENSITIVE RESIN COMPOSITION, PLATING METHOD, AND METHOD FOR PRODUCING METAL PATTERN | 三菱製紙株式会社 | 2020-02-06 | — | — | WO | disclosed |
| EP-1455740-A1 | HAIR TREATMENT COMPOSITION COMPRISING COMPOSITE PARTICLES OF CLAY AND CHARGED ORGANIC MOLECULE | Unilever Plc (GB) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003047541-A1 | HAIR TREATMENT COMPOSITION COMPRISING COMPOSITE PARTICLES OF CLAY AND CHARGED ORGANIC MOLECULE | UNILEVER PLC (GB) | 2003-06-12 | — | — | WO | disclosed |
| WO-2002067882-A1 | HAIR COLORANT IN THE FORM OF A CREAMY PERMANENT MOUSSE OR A STABLE FOAMED CREME COLORANT | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-06 | — | — | WO | disclosed |
| US-5909114-A | Coulometric analysis method and a device therefor | NAKANO VINEGAR CO., LTD. (JP) | 1999-06-01 | — | — | US | disclosed |
| US-5790627-A | Method and apparatus for observing a specimen using an X-ray microscope | RESEARCH DEVELOPMENT CORP. (JP) | 1998-08-04 | — | — | US | disclosed |
| US-5726565-A | FOR QUANTITATIVE DETERMINATION OF A SAMPLE SUBSTANCE | NAKANO VINEGAR CO., LTD. (JP) | 1998-03-10 | — | — | US | disclosed |
| EP-0600607-A2 | Coulometric analysis method and a device therefor | NAKANO VINEGAR CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |