SCHEMBL172197

SCHEMBL172197

C1=CC2Nc3ccccc3OC2C=C1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.36
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
ALOX5 P09917 1/20 0.33
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
CYB5R3 P00387 1/20 0.31
NISCH Q9Y2I1 1/20 0.30
ME2 P23368 1/20 0.30
ME1 P48163 1/20 0.30
ME3 Q16798 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6829790 0.75 PARP1 (0.32) PARP1MEN1KMT2ALMNAMAPT
SCHEMBL8620692 0.73 CREBBP (0.37) MEN1KMT2AMAPTBRD4CREBBP
SCHEMBL13138773 0.73 ABCG2 (0.39) NISCHME2ME1ME3
SCHEMBL22133445 0.71
SCHEMBL22133439 0.71
SCHEMBL22133437 0.70 NR4A1 (0.33) MEN1KMT2AMAPTKDM4EGAA
SCHEMBL11993892 0.70 OXTR (0.37) GAANISCH
SCHEMBL8651078 0.69 GAA (0.57) PARP1MEN1KMT2ALMNAMAPT
SCHEMBL17425300 0.68 KEAP1 (0.37) ME2ME1ME3
SCHEMBL22134197 0.66 MAPT (0.37) PARP1MEN1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0767809-B1 CURE-INDICATING MOLDING AND COATING COMPOSITION MINNESOTA MINING & MFG (US) 2004-01-21 EP claimed
WO-2024059825-A1 SYSTEMS AND METHODS FOR QUANTIFYING USER OBSERVED VISUALIZATION OF FLUORESCENCE IMAGING AGENTS STRYKER CORPORATION (US) 2024-03-21 WO disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
WO-2023116124-A1 ORGANIC-INORGANIC HYBRID SHORT-WAVE INFRARED PHOTOELECTRIC DETECTOR, ARRAY FORMED BY SAME, AND PREPARATION METHOD RELATED THERETO 广州光达创新科技有限公司 2023-06-29 WO disclosed
EP-3821249-B1 SPECIFIC BINDING CHEMILUMINESCENT ASSAY 3M INNOVATIVE PROPERTIES CO (US) 2022-06-29 EP disclosed
CN-110914328-B Indicator system 科思创德国股份有限公司 2022-05-13 CN disclosed
US-11320424-B2 Specific binding chemiluminescent assay 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-05-03 US disclosed
CN-110945048-B Acidic indicator system 科思创德国股份有限公司 2022-03-15 CN disclosed
EP-3960744-A1 CYCLOALKANE-CONDENSED POLYCYCLIC AROMATIC COMPOUND Kwansei Gakuin Educational Foundation (JP) 2022-03-02 EP disclosed
US-20220037591-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-02-03 US disclosed
US-20090176162-A1 LITHIUM RECHARGEABLE ELECTROCHEMICAL CELL DOW GLOBAL TECHNOLOGIES LLC 2009-07-09 US disclosed
US-20090176162-A1 LITHIUM RECHARGEABLE ELECTROCHEMICAL CELL DOW GLOBAL TECHNOLOGIES LLC 2009-07-09 US disclosed
WO-2008047324-A2 NANOTUBE WIRING HIGH POWER LITHIUM S.A. (CH) 2008-04-24 WO disclosed
WO-2007116363-A2 LITHIUM RECHARGEABLE ELECTROCHEMICAL CELL HIGH POWER LITHIUM S.A. (CH) 2007-10-18 WO disclosed
WO-2007107961-A1 LIQUID CHARGE TRANSPORTING MATERIAL ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2007-09-27 WO disclosed
EP-1837929-A1 Liquid Charge Transporting Material Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) 2007-09-26 EP disclosed
US-7244551-B2 Silver halide color photosensitive material FUJIFILM CORPORATION (JP) 2007-07-17 US disclosed
US-7244551-B2 Silver halide color photosensitive material FUJIFILM CORPORATION (JP) 2007-07-17 US disclosed
US-20070034512-A1 Biosensor and method for producing the same ARKRAY, INC. (JP) 2007-02-15 US disclosed
EP-1679508-A1 BIOSENSOR AND METHOD FOR PREPARATION THEREOF Arkray, Inc. (JP) 2006-07-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 PARP1 895/4885MEN1 549/4885KMT2A 2002/4885
US-20220037591-A1 Polycyclic aromatic compound F11, C1R, RNF31 PARP1 895/4885MEN1 549/4885KMT2A 2002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.