Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24445379 | 1.00 | LMNA (0.46) | LMNAMAPK1KMT2AHPGDCES2 | |
| SCHEMBL11358787 | 0.81 | ALDH1A1 (0.40) | LMNAKMT2AHPGDCYP3A4CYP2C19 | |
| SCHEMBL5565864 | 0.80 | KMT2A (0.47) | LMNAKMT2ATSHRMEN1KDM4E | |
| SCHEMBL6293947 | 0.79 | LMNA (0.52) | LMNAMAPK1KMT2AHPGDCES2 | |
| SCHEMBL5094455 | 0.78 | KMT2A (0.45) | LMNAKMT2AADRA2CTSHRCHRM2 | |
| SCHEMBL9098391 | 0.78 | KMT2A (0.45) | LMNAKMT2AADRA2CTSHRCHRM2 | |
| SCHEMBL7309316 | 0.77 | KMT2A (0.44) | LMNAKMT2AADRA2CTSHRCHRM2 | |
| Mandelic Acid, Methyl Ester SCHEMBL186900 | 0.74 | KMT2A (0.67) | LMNAMAPK1KMT2AHPGDCES2 | |
| SCHEMBL19254707 | 0.74 | HPGD (0.52) | LMNAMAPK1KMT2AHPGDCES2 | |
| Mandelic Acid, Methyl Ester SCHEMBL28228867 | 0.74 | KMT2A (0.67) | LMNAMAPK1KMT2AHPGDCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743944-B1 | FORMING DIASTEREOMERIC SALT OF RACEMIC 4-AMINO-2-METHYL-BUTANE-1-OL AND OPTICALLY ACTIVE ORGANIC ACID; CRYSTALLI-ZATION; ALKALI SOLUTION DECOMPOSITION | MITSUBISHI RAYON CO., LTD. (JP) | 2004-06-01 | — | — | US | disclosed |
| EP-1219593-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINOALCOHOL | Mitsubishi Rayon Co., Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |