5-Methoxytryptamine

5-Methoxytryptamine

SCHEMBL6830006

CNC(=O)O.COc1ccc2[nH]cc(CCN)c2c1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.78
HTR2A P28223 3/20 0.78
HTR1A P08908 3/20 0.78
HTR1D P28221 2/20 0.78
HTR1B P28222 2/20 0.78
MAPT P10636 1/20 0.78
TSHR P16473 1/20 0.78
NFKB1 P19838 1/20 0.78
HTR2C P28335 1/20 0.78
HTR7 P34969 1/20 0.78
HTR6 P50406 1/20 0.78
HTR4 Q13639 1/20 0.78
TRPM8 Q7Z2W7 1/20 0.78
BLM P54132 2/20 0.76
PMP22 Q01453 2/20 0.76
NPSR1 Q6W5P4 1/20 0.76
MTNR1A P48039 5/20 0.65
MTNR1B P49286 3/20 0.65
CYP2C9 P11712 1/20 0.65
CYP2C19 P33261 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
5-Methoxytryptamine SCHEMBL27094903 0.91 HTR1A (0.84) CYP1A2HTR2AHTR1AHTR1DHTR1B
5-Methoxytryptamine SCHEMBL30812526 0.91 HTR1A (0.84) CYP1A2HTR2AHTR1AHTR1DHTR1B
5-Methoxytryptamine SCHEMBL29390103 0.88 HTR1A (1.00) CYP1A2HTR2AHTR1AHTR1DHTR1B
5-Methoxytryptamine SCHEMBL41982 0.88 HTR1A (1.00) CYP1A2HTR2AHTR1AHTR1DHTR1B
5-Methoxytryptamine SCHEMBL7094587 0.88 HTR1A (0.78) CYP1A2HTR2AHTR1AHTR1DHTR1B
5-Methoxytryptamine SCHEMBL7094589 0.88 HTR1A (0.78) CYP1A2HTR2AHTR1AHTR1DHTR1B
5-Methoxytryptamine SCHEMBL30933118 0.88 HTR1A (0.78) CYP1A2HTR2AHTR1AHTR1DHTR1B
5-Methoxytryptamine SCHEMBL31240192 0.88 HTR1A (0.78) CYP1A2HTR2AHTR1AHTR1DHTR1B
5-Methoxytryptamine SCHEMBL130877 0.87 HTR1A (0.97) CYP1A2HTR2AHTR1AHTR1DHTR1B
5-Methoxytryptamine SCHEMBL31109114 0.87 NPSR1 (1.00) CYP1A2HTR2AHTR1AHTR1DHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004075847-A2 METHODS AND COMPOUNDS FOR THE TREATMENT OF Aß­ ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS MESSAGE PHARMACEUTICALS, INC. (US) 2004-09-10 WO disclosed