Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6809539 | 0.99 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL6814161 | 0.93 | OPRM1 (0.38) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6813446 | 0.91 | KDM4E (0.35) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL6809568 | 0.91 | KDM4E (0.35) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6813493 | 0.90 | MEN1 (0.37) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL6812365 | 0.90 | MAPT (0.35) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6813100 | 0.90 | MAPT (0.35) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL6809656 | 0.89 | NR1I2 (0.38) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6813459 | 0.89 | OPRM1 (0.37) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL6826601 | 0.88 | OPRM1 (0.41) | ALDH1A1MAPTHPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052879-A1 | THIOPHENEDERIVATIVES FOR THE TREATMENT OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC. (CA) | 2004-06-24 | — | — | WO | disclosed |