Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829764 | 0.92 | NR1I2 (0.36) | NR1I2KDM4EHTTATMOPRM1 | |
| SCHEMBL6814161 | 0.91 | OPRM1 (0.38) | NR1I2KDM4EHTTATMOPRM1 | |
| Hydrochloric Acid SCHEMBL6813493 | 0.90 | MEN1 (0.37) | NR1I2KDM4EHTTATMOPRM1 | |
| SCHEMBL6830100 | 0.89 | ALDH1A1 (0.40) | NR1I2KDM4EHTTATMOPRM1 | |
| SCHEMBL6826601 | 0.88 | OPRM1 (0.41) | NR1I2KDM4EHTTATMOPRM1 | |
| Hydrochloric Acid SCHEMBL6814172 | 0.88 | KDM4E (0.35) | NR1I2KDM4EHTTATMOPRM1 | |
| Hydrochloric Acid SCHEMBL6809539 | 0.88 | ALDH1A1 (0.39) | NR1I2KDM4EHTTATMOPRM1 | |
| Hydrochloric Acid SCHEMBL6812271 | 0.88 | OPRM1 (0.40) | NR1I2KDM4EHTTATMOPRM1 | |
| SCHEMBL6809568 | 0.88 | KDM4E (0.35) | NR1I2KDM4EHTTATMOPRM1 | |
| Hydrochloric Acid SCHEMBL6813446 | 0.88 | KDM4E (0.35) | NR1I2KDM4EHTTATMOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040192707-A1 | Compounds and methods for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC. (CA) | 2004-09-30 | — | — | US | disclosed |
| WO-2004052879-A1 | THIOPHENEDERIVATIVES FOR THE TREATMENT OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC. (CA) | 2004-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192707-A1 | Compounds and methods for the treatment or prevention of Flavivirus infections | ZC3HAV1, HAVCR2, MAVS | NR1I2 561/4885KDM4E 3607/4885HTT 2977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.