Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | MMP7 | P09237 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830116 | 0.93 | KDM4E (0.51) | IDO1HRH3SLC2A1MMP1MMP3 | |
| SCHEMBL6826756 | 0.88 | DRD2 (0.54) | SLC2A1MMP1MMP3MMP7MMP9 | |
| SCHEMBL6921864 | 0.88 | HRH3 (0.51) | IDO1HRH3SLC2A1LMNAALOX5 | |
| SCHEMBL6826439 | 0.88 | LMNA (0.50) | HRH3SLC2A1LMNAALOX5NOD2 | |
| SCHEMBL6829317 | 0.87 | HTR6 (0.49) | IDO1HRH3SLC2A1MMP1MMP3 | |
| SCHEMBL6826373 | 0.87 | HRH3 (0.58) | IDO1HRH3SLC2A1ALDH1A1PKM | |
| SCHEMBL6831430 | 0.87 | SLC2A1 (0.55) | HRH3SLC2A1ALDH1A1L3MBTL1HTR6 | |
| SCHEMBL7068535 | 0.85 | HTR6 (0.54) | HRH3SLC2A1MMP1MMP3MMP7 | |
| SCHEMBL6826453 | 0.84 | PPARG (0.50) | IDO1HRH3SLC2A1ALDH1A1LMNA | |
| SCHEMBL6831422 | 0.79 | HTR6 (0.47) | SLC2A1LMNAL3MBTL1HTR6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | claimed |
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | disclosed |