Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTPRB | P23467 | 2/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830534 | 0.88 | LTB4R2 (0.50) | HTTRAB9APTPRBLTB4R2RIPK1 | |
| SCHEMBL6830347 | 0.88 | HTT (0.52) | HTTRAB9AALDH1A1PTPRBLTB4R2 | |
| SCHEMBL6831396 | 0.86 | RAB9A (0.62) | HTTRAB9ANPC1ALDH1A1PAX8 | |
| SCHEMBL1924545 | 0.85 | LTB4R2 (0.51) | HTTRAB9ANPC1ALDH1A1GLA | |
| SCHEMBL4237307 | 0.83 | ALDH1A1 (0.54) | HTTRAB9ANPC1ALDH1A1GLA | |
| SCHEMBL28986105 | 0.81 | NPC1 (0.61) | HTTRAB9ANPC1ALDH1A1GLA | |
| SCHEMBL1927016 | 0.80 | ALDH1A1 (0.69) | HTTRAB9ANPC1ALDH1A1GLA | |
| SCHEMBL4242009 | 0.80 | NPC1 (0.59) | HTTRAB9ANPC1ALDH1A1GLA | |
| SCHEMBL5766172 | 0.79 | HTT (0.47) | HTTRAB9ANPC1LTB4R2GAA | |
| SCHEMBL4237595 | 0.76 | CNR2 (0.58) | HTTRAB9ANPC1ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461336-A2 | 1-ALKYL-1-AZONIABICYCLO (2.2.2) OCTANE CARBAMATE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003053966-A2 | 1-ALKYL-1-AZONIABICYCLO [2.2.2] OCTANE CARBAMATE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2003-07-03 | — | — | WO | disclosed |