Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830534 | 0.86 | LTB4R2 (0.50) | RAB9AHTTKMT2AMEN1LTB4R2 | |
| SCHEMBL6830331 | 0.86 | HTT (0.55) | RAB9ANPC1HTTALDH1A1PAX8 | |
| SCHEMBL4086400 | 0.85 | RAB9A (0.56) | RAB9ANPC1HTTJAK2ALDH1A1 | |
| SCHEMBL1924742 | 0.84 | RAB9A (0.76) | RAB9ANPC1HTTJAK2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5431068 | 0.80 | RAB9A (0.65) | RAB9ANPC1HTTJAK2ALDH1A1 | |
| SCHEMBL1924545 | 0.78 | LTB4R2 (0.51) | RAB9ANPC1HTTJAK2ALDH1A1 | |
| SCHEMBL6830347 | 0.77 | HTT (0.52) | RAB9AHTTALDH1A1KMT2AMEN1 | |
| SCHEMBL4092097 | 0.77 | PTGDR2 (0.57) | RAB9ANPC1HTTJAK2ALDH1A1 | |
| SCHEMBL12764035 | 0.76 | TSPO (0.77) | RAB9ANPC1HTTJAK2ALDH1A1 | |
| SCHEMBL9547612 | 0.75 | ALDH1A1 (0.57) | RAB9ANPC1HTTJAK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461336-A2 | 1-ALKYL-1-AZONIABICYCLO (2.2.2) OCTANE CARBAMATE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003053966-A2 | 1-ALKYL-1-AZONIABICYCLO [2.2.2] OCTANE CARBAMATE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2003-07-03 | — | — | WO | disclosed |