SCHEMBL6830332

SCHEMBL6830332

O=C(O)Nc1ccccc1Cc1ccc(F)c(F)c1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.49
MAPT P10636 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
PKM P14618 1/20 0.45
KCNQ2 O43526 1/20 0.44
PTPN1 P18031 1/20 0.42
RAB9A P51151 3/20 0.41
NPC1 O15118 1/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 3/20 0.41
MAOB P27338 1/20 0.41
HTT P42858 1/20 0.40
TRPV1 Q8NER1 1/20 0.40
CXCL8 P10145 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4237309 0.83 L3MBTL1 (0.56) L3MBTL1MAPTSMN1; SMN2PKMRAB9A
SCHEMBL4172605 0.81 L3MBTL1 (0.70) L3MBTL1MAPTSMN1; SMN2PKMRAB9A
SCHEMBL4242010 0.80 L3MBTL1 (0.56) L3MBTL1MAPTSMN1; SMN2RAB9ANPC1
SCHEMBL4250189 0.80 RAB9A (0.50) L3MBTL1MAPTSMN1; SMN2PKMPTPN1
SCHEMBL27547012 0.79 L3MBTL1 (0.68) L3MBTL1MAPTSMN1; SMN2PKMRAB9A
Hydrochloric Acid SCHEMBL11164652 0.79 L3MBTL1 (0.68) L3MBTL1MAPTSMN1; SMN2PKMRAB9A
SCHEMBL4622869 0.79 L3MBTL1 (0.56) L3MBTL1MAPTSMN1; SMN2KMT2AMEN1
SCHEMBL4237601 0.78 L3MBTL1 (0.62) L3MBTL1SMN1; SMN2PKMRAB9ANPC1
SCHEMBL4621396 0.78 L3MBTL1 (0.58) L3MBTL1PKMKMT2AMEN1ALDH1A1
SCHEMBL12510352 0.75 L3MBTL1 (0.54) L3MBTL1MAPTALDH1A1MAOBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1461336-A2 1-ALKYL-1-AZONIABICYCLO (2.2.2) OCTANE CARBAMATE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS LABORATORIOS S.A.L.V.A.T., S.A. (ES) 2004-09-29 EP disclosed
WO-2003053966-A2 1-ALKYL-1-AZONIABICYCLO [2.2.2] OCTANE CARBAMATE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS LABORATORIOS S.A.L.V.A.T., S.A. (ES) 2003-07-03 WO disclosed