Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172605 | 0.90 | L3MBTL1 (0.70) | L3MBTL1ALDH1A1HPGDPOLBMAPT | |
| SCHEMBL4250189 | 0.89 | RAB9A (0.50) | L3MBTL1ALDH1A1MAPTGAAHTT | |
| Hydrochloric Acid SCHEMBL11164652 | 0.88 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1HPGDPOLBMAPT | |
| SCHEMBL27547012 | 0.88 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1HPGDPOLBMAPT | |
| SCHEMBL22210650 | 0.88 | L3MBTL1 (0.77) | L3MBTL1ALDH1A1HPGDPOLBMAPT | |
| SCHEMBL22210638 | 0.88 | HDAC3 (0.53) | L3MBTL1ALDH1A1HPGDPOLBHDAC3 | |
| SCHEMBL948318 | 0.87 | MAPT (0.59) | L3MBTL1ALDH1A1HPGDPOLBHDAC3 | |
| Hydrochloric Acid SCHEMBL22346017 | 0.85 | MAPT (0.58) | L3MBTL1ALDH1A1HPGDPOLBHDAC3 | |
| SCHEMBL648646 | 0.85 | ALDH1A1 (0.66) | L3MBTL1ALDH1A1HPGDPOLBHDAC3 | |
| SCHEMBL4621396 | 0.84 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1HPGDPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420013-B1 | Process for hydrogenating aromatic urethanes in the presence of a supported ruthenium catalyst | EVONIK DEGUSSA GMBH (DE) | 2008-04-02 | — | — | EP | claimed |
| EP-1420012-B1 | Process for the preparation of aliphatic isocyanates from aromatic isocyanates | DEGUSSA (DE) | 2006-11-02 | — | — | EP | claimed |
| US-6924385-B2 | Method for synthesis of aliphatic isocyanates from aromatic isocyanates | DEGUSSA AG (DE) | 2005-08-02 | — | — | US | claimed |
| US-6809215-B2 | SUCH AS CONVERSION OF DIBUTYL 4,4'-METHYLENEDICARBANILATE TO DIBUTYL 4,4'-METHYLENEDICYCLOHEXYLCARBAMATE WITH LOW TRANS-TRANS ISOMER CONTENT | DEGUSSA AG (DE) | 2004-10-26 | — | — | US | claimed |
| US-20040097752-A1 | Method for synthesis of aliphatic isocyanates from aromatic isocyanates | DEGUSSA AG (DE) | 2004-05-20 | — | — | US | claimed |
| US-20040097661-A1 | Method for hydrogenation of aromatic urethanes in the presence of a supported rutheniun catalyst | DEGUSSA AG (DE) | 2004-05-20 | — | — | US | claimed |
| EP-1420012-A1 | Process for the preparation of aliphatic isocyanates from aromatic isocyanates | Degussa AG (DE) | 2004-05-19 | — | — | EP | claimed |
| EP-1420013-A1 | Process for hydrogenating aromatic urethanes in the presence of a supported ruthenium catalyst | Degussa AG (DE) | 2004-05-19 | — | — | EP | claimed |
| EP-0027330-B1 | PROCESS FOR THE PRODUCTION OF METHYLENEDICARBANILATES AND THE COMPOUNDS THUS OBTAINED | MITSUBISHI KASEI CORPORATION (JP) | 1984-12-12 | — | — | EP | claimed |
| US-4476317-A | HETEROPOLYMOLYBDIC ACID OR HETEROPOLYTUNGSTIC ACID | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1984-10-09 | — | — | US | claimed |
| EP-0027330-A1 | Process for the production of methylenedicarbanilates and the compounds thus obtained | MITSUBISHI KASEI CORPORATION (JP) | 1981-04-22 | — | — | EP | claimed |
| JP-3083959-A | — | — | None | — | — | JP | disclosed |
| JP-56057758-A | — | — | None | — | — | JP | disclosed |
| JP-56057759-A | — | — | None | — | — | JP | disclosed |
| JP-56057761-A | — | — | None | — | — | JP | disclosed |
| JP-S5657759-A | PREPARATION OF METHYLENEDICARBANILATE | MITSUBISHI CHEM IND LTD | 1981-05-20 | — | — | JP | disclosed |
| JP-S5657758-A | PREPARATION OF METHYLENEDICARBANILATE | MITSUBISHI CHEM IND LTD | 1981-05-20 | — | — | JP | disclosed |
| EP-0027330-A1 | Process for the production of methylenedicarbanilates and the compounds thus obtained | MITSUBISHI KASEI CORPORATION (JP) | 1981-04-22 | — | — | EP | disclosed |
| EP-0027330-A1 | Process for the production of methylenedicarbanilates and the compounds thus obtained | MITSUBISHI KASEI CORPORATION (JP) | 1981-04-22 | — | — | EP | disclosed |
| EP-0027330-A1 | Process for the production of methylenedicarbanilates and the compounds thus obtained | MITSUBISHI KASEI CORPORATION (JP) | 1981-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097752-A1 | Method for synthesis of aliphatic isocyanates from aromatic isocyanates | DBI, ALKBH3, ECI1 | L3MBTL1 3094/4885ALDH1A1 921/4885HPGD 1051/4885 |
| US-20040097661-A1 | Method for hydrogenation of aromatic urethanes in the presence of a supported rutheniun catalyst | HRH4, BET1, HRH3 | L3MBTL1 4008/4885ALDH1A1 2849/4885HPGD 597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.