Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831040 | 0.81 | ALDH1A1 (0.47) | HTTALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL27620938 | 0.79 | ALDH1A1 (0.42) | HTTALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5438790 | 0.73 | TRPM8 (0.58) | TSHRCHRM2CHRM1CHRM3THRB | |
| SCHEMBL11287043 | 0.73 | ALDH1A1 (0.58) | HTTALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL1927016 | 0.73 | ALDH1A1 (0.69) | HTTALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL4242009 | 0.73 | NPC1 (0.59) | HTTALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL10888085 | 0.70 | KMT2A (0.48) | HTTALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5973257 | 0.70 | KMT2A (0.51) | HTTALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9160381 | 0.68 | ALDH1A1 (0.56) | HTTALDH1A1RAB9ASMN1; SMN2KMT2A | |
| Carbamic Acid SCHEMBL6468271 | 0.68 | NPC1 (0.62) | HTTALDH1A1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461336-A2 | 1-ALKYL-1-AZONIABICYCLO (2.2.2) OCTANE CARBAMATE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003053966-A2 | 1-ALKYL-1-AZONIABICYCLO [2.2.2] OCTANE CARBAMATE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2003-07-03 | — | — | WO | disclosed |