Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16853618 | 0.84 | SOS1 (0.39) | HPGDMAPTHSD17B10SMN1; SMN2NOTUM | |
| SCHEMBL27302875 | 0.82 | HPGD (0.41) | HPGDMAPTHSD17B10SMN1; SMN2NOTUM | |
| SCHEMBL31069592 | 0.78 | POLB (0.41) | TAS1R3TAS1R1TAS1R2HPGDMAPT | |
| SCHEMBL29133051 | 0.78 | MAPT (0.41) | HPGDMAPTHSD17B10SMN1; SMN2NOTUM | |
| SCHEMBL24717415 | 0.76 | TPMT (0.41) | HPGDMAPTHSD17B10SMN1; SMN2NOTUM | |
| SCHEMBL19840236 | 0.76 | HPGD (0.38) | HPGDMAPTHSD17B10SMN1; SMN2NOTUM | |
| SCHEMBL6923912 | 0.76 | CA2 (0.43) | HPGDMAPTHSD17B10TSHRTPMT | |
| SCHEMBL18797706 | 0.76 | CA12 (0.40) | HPGDMAPTEPAS1HSD17B10NOTUM | |
| SCHEMBL25280044 | 0.76 | LMNA (0.40) | HPGDMAPTEPAS1SMN1; SMN2NOTUM | |
| SCHEMBL20396954 | 0.76 | MAPT (0.41) | HPGDMAPTHSD17B10SMN1; SMN2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |