Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804695 | 0.86 | CA2 (0.42) | CA2CA4HSD17B10TPMTTSHR | |
| SCHEMBL16815606 | 0.84 | CA2 (0.36) | CA2CA4HSD17B10ILKPTGS2 | |
| SCHEMBL15561614 | 0.79 | CA2 (0.43) | CA2CA4HSD17B10TPMTTSHR | |
| SCHEMBL29582345 | 0.79 | CA2 (0.43) | CA2CA4HSD17B10TPMTTSHR | |
| SCHEMBL5704414 | 0.79 | CA2 (0.39) | CA2CA4HSD17B10TPMTTSHR | |
| SCHEMBL9549445 | 0.78 | CA2 (0.38) | CA2CA4HSD17B10TPMTPTGS2 | |
| SCHEMBL6830349 | 0.76 | TAS1R3 (0.36) | HSD17B10TPMTTSHRMAPTHPGD | |
| SCHEMBL23461762 | 0.75 | ALOX5AP (0.38) | CA2CA4NQO2PTGS2MAPT | |
| SCHEMBL3836832 | 0.75 | ALOX5AP (0.35) | CA2CA4NQO2PTGS2MAPT | |
| SCHEMBL27628106 | 0.75 | CA2 (0.43) | CA2CA4HSD17B10TPMTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |