SCHEMBL6830401

SCHEMBL6830401

Nc1ccc2ccccc2c1C(O)=S

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
HSD17B10 Q99714 5/20 0.45
HPGD P15428 3/20 0.45
TSHR P16473 2/20 0.45
CYP3A4 P08684 1/20 0.45
KEAP1 Q14145 1/20 0.45
HPRT1 P00492 2/20 0.42
CYP2A6 P11509 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KDM4E B2RXH2 3/20 0.39
MEN1 O00255 2/20 0.39
GLA P06280 2/20 0.39
KMT2A Q03164 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 1/20 0.39
PTPN22 Q9Y2R2 1/20 0.38
HDAC3 O15379 1/20 0.38
IDO1 P14902 1/20 0.38
EP300 Q09472 1/20 0.38
KAT2B Q92831 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL344096 0.80 HSD17B10 (0.59) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL5047197 0.78 HSD17B10 (0.57) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL8665134 0.78 PTPN22 (0.54) ALDH1A1HSD17B10HPGDTSHRCYP2A6
SCHEMBL10775545 0.77 GAA (0.51) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL8016926 0.77 MAPT (0.48) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL4619493 0.76 ALDH1A1 (0.45) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL3071557 0.75 KMT2A (0.32) HSD17B10CYP3A4KEAP1TDP1KDM4E
SCHEMBL23391023 0.74 NCEH1 (0.51) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL9762785 0.74 ALDH1A1 (0.43) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL6925516 0.74 MAPT (0.46) ALDH1A1CYP3A4TDP1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472319-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2004-11-03 EP disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed