SCHEMBL6925516

SCHEMBL6925516

NNC(=O)c1ccc2ccccc2c1C(O)=S

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.46
GAA P10253 3/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
MITF O75030 1/20 0.45
NCOA1 Q15788 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
NCOA3 Q9Y6Q9 1/20 0.45
WDR5 P61964 1/20 0.45
LDHA P00338 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
PLG P00747 2/20 0.42
KLK1 P06870 2/20 0.42
KLK6 Q92876 2/20 0.42
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL856182 0.87 MAPT (0.50) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL9471969 0.83 MAPT (0.47) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL5480836 0.81 WDR5 (0.56) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL712806 0.79 MAPT (0.50) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL1638772 0.78 LDHA (0.65) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL10775545 0.75 GAA (0.51) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL145153 0.74 HDAC8 (0.69) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL6830401 0.74 ALDH1A1 (0.45) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL712805 0.74 WDR5 (0.51) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL1639535 0.73 ALOX15 (0.55) MAPTGAAKDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472319-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2004-11-03 EP disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed