Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL344096 | 0.82 | HSD17B10 (0.59) | ALDH1A1HSD17B10HPGDTSHRCYP3A4 | |
| SCHEMBL4619493 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HSD17B10HPGDTSHRCYP3A4 | |
| SCHEMBL23391023 | 0.81 | NCEH1 (0.51) | ALDH1A1HSD17B10HPGDTSHRCYP3A4 | |
| SCHEMBL5047197 | 0.81 | HSD17B10 (0.57) | ALDH1A1HSD17B10HPGDTSHRCYP3A4 | |
| SCHEMBL10775545 | 0.79 | GAA (0.51) | ALDH1A1HSD17B10HPGDTSHRCYP3A4 | |
| SCHEMBL5047194 | 0.79 | HSD17B10 (0.42) | ALDH1A1HSD17B10HPGDTSHRCYP3A4 | |
| SCHEMBL8016926 | 0.79 | MAPT (0.48) | ALDH1A1HSD17B10HPGDTSHRCYP3A4 | |
| SCHEMBL3918323 | 0.78 | ABCG2 (0.54) | ALDH1A1HSD17B10HPGDKDM4EGLA | |
| SCHEMBL6609007 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HPGDTSHRKDM4E | |
| SCHEMBL29819980 | 0.78 | WDR5 (0.50) | ALDH1A1HSD17B10HPGDTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023325-A | Colorfastness, photostability | CIBA-GEIGY CORPORATION (US) | 1991-06-11 | — | — | US | disclosed |
| US-5023326-A | Monoazo, naphthol, aniline and triazine red dyes; colorfastness; cotton | CIBA-GEIGY CORPORATION (US) | 1991-06-11 | — | — | US | disclosed |
| US-5003052-A | Monoazo fiber reactive dye for cellulose, polyamides, wool, silk, polyurethanes and leather | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-4786721-A | DYEING OR PRINTING CELLULOSE FIBERS | CIBA-GEIGY CORPORATION (US) | 1988-11-22 | — | — | US | disclosed |
| US-4766206-A | Reactive dyestuffs comprising a vinylsulfonylalkylaminocarbonyl moiety | CIBA-GEIGY CORPORATION (US) | 1988-08-23 | — | — | US | disclosed |