Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | TYK2 | P29597 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7131171 | 0.82 | EGFR (0.55) | EGFRMEN1GAAKMT2ANPC1 | |
| SCHEMBL3223241 | 0.80 | SMN1; SMN2 (0.54) | EGFRKDM4EGAANPC1RAB9A | |
| SCHEMBL6826031 | 0.76 | SCN10A (0.47) | KDM4EMEN1GAAKMT2ANPC1 | |
| SCHEMBL29377185 | 0.74 | BRAF (0.41) | EGFRMEN1KMT2AMAPT | |
| SCHEMBL23779466 | 0.73 | SMN1; SMN2 (0.47) | EGFRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL27824692 | 0.73 | PNLIP (0.54) | KDM4EKMT2ASMN1; SMN2AHRMAPT | |
| SCHEMBL6649755 | 0.73 | PPARG (0.49) | EGFRKDM4EMEN1GAAKMT2A | |
| SCHEMBL11557801 | 0.72 | EGFR (0.56) | EGFRKDM4EMEN1GAAKMT2A | |
| SCHEMBL27803848 | 0.72 | RAB9A (0.56) | KDM4EMEN1GAAKMT2ANPC1 | |
| SCHEMBL6644545 | 0.71 | CHRNB2 (0.46) | NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |