SCHEMBL6830892

SCHEMBL6830892

CC(COC(=O)OC[C@H]1O[C@@H](n2cnc3c(NC(=O)COc4ccccc4)ncnc32)C[C@@H]1O)c1cc(Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 4/20 0.43
ADORA3 P0DMS8 3/20 0.38
ADORA2B P29275 2/20 0.38
ADORA1 P30542 2/20 0.38
P2RY12 Q9H244 2/20 0.37
ENPP1 P22413 2/20 0.36
P2RY1 P47900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6834210 0.93 SLC29A1 (0.43) SLC29A1ADORA3ADORA2BADORA1P2RY12
SCHEMBL6835937 0.93 SLC29A1 (0.43) SLC29A1ADORA3ADORA2BADORA1P2RY12
SCHEMBL6892237 0.93 SLC29A1 (0.45) SLC29A1ADORA3ADORA2BADORA1P2RY12
SCHEMBL8380398 0.81 SLC29A1 (0.49) SLC29A1ADORA3ADORA2BADORA1P2RY12
SCHEMBL6892233 0.80 TAS1R3 (0.41) SLC29A1ADORA3ADORA2BADORA1
SCHEMBL7040477 0.79 SLC29A1 (0.57) SLC29A1ADORA3P2RY12
SCHEMBL6890238 0.77 POLB (0.39)
SCHEMBL6896046 0.76 SLC29A1 (0.41) SLC29A1ADORA3ADORA2BADORA1
SCHEMBL7035979 0.76 SLC29A1 (0.57) SLC29A1ADORA3ADORA1
SCHEMBL9446435 0.76 SLC29A1 (0.57) SLC29A1ADORA3ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6750335-B2 NUCLEOSIDE FOR USE IN THE GENERATION OF PREFERENTIAL OLIGONUCEOTIDES NIGU CHEMIE GMBH (DE) 2004-06-15 US disclosed
EP-1224198-B1 NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTING GROUPS NIGU CHEMIE GMBH (DE) 2003-04-23 EP disclosed
US-20020146737-A1 Nucleoside derivatives with photolabile protective groups NIGU CHEMIE GMBH (DE) 2002-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020146737-A1 Nucleoside derivatives with photolabile protective groups XRN2, XPA, NSUN2 SLC29A1 469/4885ADORA3 285/4885ADORA2B 507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.