Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 6/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895269 | 0.88 | KDM4E (0.46) | SLC29A1ADORA1ADORA3ADORA2B | |
| SCHEMBL6891890 | 0.85 | POLB (0.48) | — | |
| SCHEMBL6892237 | 0.83 | SLC29A1 (0.45) | SLC29A1ADORA1ADORA3ADORA2B | |
| SCHEMBL4627842 | 0.77 | TYMP (0.43) | SLC29A1ADORA3 | |
| SCHEMBL6835937 | 0.76 | SLC29A1 (0.43) | SLC29A1ADORA1ADORA3ADORA2B | |
| SCHEMBL6830892 | 0.76 | SLC29A1 (0.43) | SLC29A1ADORA1ADORA3ADORA2B | |
| SCHEMBL6834210 | 0.76 | SLC29A1 (0.43) | SLC29A1ADORA1ADORA3ADORA2B | |
| SCHEMBL7047161 | 0.76 | POLB (0.39) | — | |
| SCHEMBL9446435 | 0.71 | SLC29A1 (0.57) | SLC29A1ADORA1ADORA3 | |
| SCHEMBL7035979 | 0.71 | SLC29A1 (0.57) | SLC29A1ADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212338-B1 | Nucleoside derivatives with photolabile protective groups | DEUTSCHES KREBSFORSCH (DE) | 2012-11-21 | — | — | EP | disclosed |
| US-6756492-B1 | Nucleoside derivatives with photo-unstable protective groups | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUND DES OFFENTLICHEN RECHTS (DE) | 2004-06-29 | — | — | US | disclosed |