Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 3/20 | 0.41 |
| ▸ | PRKCI | P41743 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830990 | 0.82 | MEN1 (0.40) | PRKCIKDM4EKMT2ANPC1MEN1 | |
| SCHEMBL6830833 | 0.81 | KDM4E (0.48) | PRKCIKDM4EKMT2ANPC1MEN1 | |
| SCHEMBL6826008 | 0.77 | SCN10A (0.61) | KMT2AMEN1KIF18AALDH1A1 | |
| SCHEMBL7079669 | 0.75 | MEN1 (0.55) | KMT2AMEN1 | |
| SCHEMBL24963302 | 0.69 | NAPRT (0.44) | PRKCIKDM4ELMNAALDH1A1GAA | |
| SCHEMBL6829379 | 0.68 | MAPT (0.46) | PRKCIKDM4EKMT2ANPC1MEN1 | |
| SCHEMBL26054706 | 0.68 | NAPRT (0.41) | KDM4ENPC1LMNAALDH1A1RAB9A | |
| SCHEMBL6644962 | 0.68 | KMT2A (0.42) | PRKCIKDM4EKMT2ANPC1MEN1 | |
| SCHEMBL3575626 | 0.67 | CHIA (0.52) | KDM4EKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL3115288 | 0.67 | NAMPT (0.49) | PRKCIKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |