Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | PRKCI | P41743 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829379 | 0.85 | MAPT (0.46) | KDM4EPRKCIKMT2AMEN1MAPT | |
| SCHEMBL6830902 | 0.81 | VCP (0.41) | KDM4EPRKCIKMT2AMEN1MAPT | |
| SCHEMBL6828993 | 0.79 | L3MBTL1 (0.39) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL7104069 | 0.78 | MEN1 (0.61) | KDM4EPRKCIKMT2AMEN1MAPT | |
| SCHEMBL24963302 | 0.75 | NAPRT (0.44) | KDM4EPRKCIMAPTALDH1A1GAA | |
| SCHEMBL6828842 | 0.75 | TRPV1 (0.58) | KDM4ENPC1RAB9ACASP3SENP8 | |
| SCHEMBL6645190 | 0.74 | MAPT (0.49) | KDM4EKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL3575626 | 0.74 | CHIA (0.52) | KDM4EKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL29448035 | 0.72 | NAPRT (0.58) | KDM4EKMT2AMAPTALDH1A1GAA | |
| SCHEMBL4290255 | 0.72 | NAPRT (0.58) | KDM4EKMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |